Celebrex (celecoxib) is a nonsteroidal anti-inflammatory drug (NSAID) belonging to the selective COX-2 inhibitor class. It is commonly used to treat pain and inflammation associated with osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. Celebrex works by inhibiting the COX-2 enzyme, which plays a key role in the production of inflammatory prostaglandins, while sparing the COX-1 enzyme that protects the stomach lining.
Celebrex is preferred in patients who require long-term NSAID therapy because it has a lower risk of causing gastrointestinal ulcers and bleeding compared to traditional NSAIDs. However, long-term use may increase the risk of cardiovascular events, so patients should be regularly monitored for heart health.
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